FEATURES OF CEREBRAL BLOOD FLOW REACTIVITY IN PATIENTS WITH POST-TRAUMATIC EPILEPSY

Authors

  • Kalashnikov V.Y.* Uzhhorod National University, Uzhhorod, Ukraine. Author
  • Oros M.M. Uzhhorod National University, Uzhhorod, Ukraine. Author
  • Stoyanov O.M. Odessa National Medical University, Odessa, Ukraine Author
  • Vastyanov R.S. Odessa National Medical University, Odessa, Ukraine Author
  • Melnik YuV. Diagnostic Center "Neuro-CardioLab", Odessa, Ukraine Author

DOI:

https://doi.org/10.65336/WJAMS.2026.3304

Keywords:

Transcranial Doppler sonography, cerebrovascular reactivity, posttraumatic epilepsy, cerebral hemodynamics

Abstract

Transcranial Doppler ultrasonography was used to examine 65 young patients with symptomatic posttraumatic partial epilepsy. Cerebral arterial blood flow velocity and reactivity to functional stress were assessed. Hyporeactivity to vasoconstrictor stress was observed in all clinical groups. Depletion of vasodilator responses was observed in patients with subcompensation and decompensation of the disease. Patients with frequent epileptic seizures showed a significant decrease in reactivity to orthostatic stress. Mild hyperreactivity to the antiorthostatic test was detected in the group of patients with clinical compensation. The hyporeactivity to functional stress in patients with epilepsy is due to the possible parasympathetic influence of the suprasegmental autonomic nervous system.

 

References

1. Antonenko, S. A. (2019). Main mechanisms and features of epileptogenesis of post-traumatic epilepsy. Journal of Education, Health and Sport, 9(10), 346-357.

2. Vastyanov, R. S., Stoyanov, A. N., Demidov, V. M., Bylsky, D. V., Antonenko, S. A., Nescoromnaya, N. V., ... & Pulyk, A. R. (2016). Повреждения травматического и гипоксического генеза: общность патогенетических механизмов= Traumatic and hypoxic damages: common pathogenetic mechanisms. Journal of Education, Health and Sport, 6(9), 285-304.

3. Stoyanov OM, Vastyanov RS, Muratova TM, Antonenko SO, Burlya OK. A.N. (2016). Comorbidive vegetative support of posttraumatic epilepsy. Experimental and clinical medicine.2 (7):194-198.

4. Vastyanov RS, Stoyanov AN, Antonenko SA, Nescoromnaya NV, Sivolap M Yu, Pulyk AR. (2016). Neurotransmitter impairment pathogenetic importance in case of brain trauma.Pathogenetic meaning broken neurotransmitter transmission in craniocerebral трамі . Journal of marine medicine. 3 (72) : 113-121.

5. Stoyanov OM , Kolesnik OO , Mashchenko SS , Antonenko SO , Kaptalan AO. (2016). The fate of the vegetative systems shodo paroxysmalities and formation post-traumatic epilepsy. Journal of Education, Health and Sport. 6 ( 11 ): 889-904 .

6. Oros MM. (2012). Correlations between data of ectroencephalography and farmacogenetics criterias in patients with epilepsy. Actual problems of transport medicine.2 (28): 56-62.

7. Dubenko A, Kalashnikov V. (1996). Peculiarities of brain hemodynamics in patients with epilepsy according to the data of Transcranial Dopplerography. European Journal of Neurology.3 (5):139.

8. Kalashnikov, V. (2016). STUDY OF THE CEREBRAL HEMODYNAMICS AND CEREBROVASCULAR REACTIVITY IN PATIENTS WITH VERTEBROGENIC CERVICOCRANIALGIA. Inter collegas, 3(4), 185-189.

Downloads

Published

2026-03-25

Issue

Section

Articles

How to Cite

[1]
Kalashnikov V.Y.*, Oros M.M., Stoyanov O.M., Vastyanov R.S., and Melnik YuV., Trans., “FEATURES OF CEREBRAL BLOOD FLOW REACTIVITY IN PATIENTS WITH POST-TRAUMATIC EPILEPSY”, WJAMS, vol. 3, no. 3, pp. 32–34, Mar. 2026, doi: 10.65336/WJAMS.2026.3304.

Similar Articles

You may also start an advanced similarity search for this article.